Program for New Century Excellent Talents in University (No. NCET-07-0378), Key Technologies Research and Development Program of Jiangsu Province, China (No. SBE200900022), National Science Fund for Distinguished Young Scholars (No. 20625619), National Basic Research Prgram of China (973 Program) (No. 2007CB714306).
Microbial catalase is an important industrial enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. This enzyme has great potential of application in food, textile and pharmaceutical industries. The production of microbial catalase has been significantly improved thanks to advances in bioprocess engineering and genetic engineering. In this paper, we review the progresses in fermentation production of microbial catalase and its application in textile industry. Among these progresses, we will highlight strain isolation, substrate and environment optimization, enzyme induction, construction of engineering strains and application process optimization. Meanwhile, we also address future research trends for microbial catalase production and its application in textile industry. Molecular modification (site-directed mutagenesis and directed revolution) will endue catalase with high pH and temperature stabilities. Improvement of catalase production, based on the understanding of induction mechanism and the process control of recombinant stain fermentation, will further accelerate the application of catalase in textile industry.
张东旭,堵国成,陈坚. 微生物过氧化氢酶的发酵生产及其在纺织工业的应用[J]. Chinese Journal of Biotechnology, 2010, 26(11): 1473-1481
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