National Natural Science Foundation of China (Nos. 21336009, 41176111, 41306124), the Fundamental Research Funds for the Central Universities (No. 2013121029).
Methane monooxygenases (MMO), regarded as “an amazing biomolecular machine”, catalyze the oxidation of methane to methanol under aerobic conditions. MMO catalyze the oxidation of methane elaborately, which is a novel way to catalyze methane to methanol. Furthermore, MMO can inspire the biomolecular machine design. In this review, we introduced MMO including structure, gene and catalytic mechanism. The history and the taxonomy of MMO were also introduced.
陆吉学,王世珍,方柏山. 生物分子机器——甲烷单加氧酶的研究进展[J]. Chinese Journal of Biotechnology, 2015, 31(7): 1015-1023
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