2014蛋白质组学专刊序言

Preface for special issue on proteomics (2014)

摘要:

蛋白质组学研究是后基因组学时代最重要的功能基因组学研究之一，与医学生物学、化学、物理学、信息学以及现代技术等关系十分密切。为了检阅近年来国内外蛋白质组学某些重要研究进展，探索其可能的应用范围，讨论其存在的问题，展望其发展前景，特组织出版“蛋白质组学专刊”。本期专刊包括综述和研究论文两部分，内容主要涉及不同物种 (包括人类、哺乳类动物、原核生物、放线菌等) 蛋白质组学研究、蛋白质组学重要方法学与技术研究 (包括串联质谱分析、尿蛋白膜保存法、定量蛋白质组学分折、meta分析等) 和蛋白质组功能与应用研究 (包括蜘蛛毒素蛋白质组、磷酸化蛋白质组、卵母细胞和早期胚胎蛋白质组、肝脏纤维化蛋白质组、分枝杆菌耐药的蛋白质组等)。

Abstract:

Proteomics is one of the most important functional genomics research in the post-genomic era, which is closely related to medical biology, chemistry, physics, information science and modern technology. Through review research progress of some important proteomics, a proteomics special issue is published so as to find problems, explore the possible applications and outlook the development prospects of proteomics. The special issue consists of reviews and original papers, mainly involving in the following aspects, i) proteomics about different species such as humans, mammals, prokaryotes and actinobacterial; ii) proteomics methodology and techniques including tandem mass spectrometry analysis, film (urimem) preservation of urine protein, quantitative proteomic analysis and meta analysis; iii) function and application of proteome such as spider (Latrodectus tredecimguttatus) toxins proteome, protein phosphorylation proteome, oocytes and early embryos proteomes, liver fibrosis proteome, drug-resistant mycobacterium tuberculosis proteome, etc.