聚羟基脂肪酸酯的研究进展

Progress on polyhydroxyalkanoates (PHA)

摘要:

微生物合成的聚羟基脂肪酸酯 (PHA) 近来正向着材料的多样性和生产技术的先进性发展。材料的多样性在多种单体及其分布、分子量、聚合方式等方面越来越细化，形成了PHA组学的概念。而合成生物学技术的应用与蓝水生物技术的出现，有望大幅度降低PHA的生产成本，更有经济性和竞争性。PHA已经有一些商业化的例子；同时，PHA在医药等领域的高附加值也被不断开发出来。

Abstract:

Microbial polyhydroxyalkanoates (PHA) has developed with more diversity and more advanced manufacturing technology. Diversity has now been reflected by diverse monomers, diverse structures and diverse polymerization modes, giving the concept of “PHAome”. In addition, the application of synthetic biology and the development of seawater-based biotechnology reduce the production cost of PHA, making PHA more economically competitive. Some examples of commercialized PHA products are described here. Besides, PHA with high value added applications has been exploited.