蓝细菌光驱固碳合成蔗糖技术的发展与展望

Cyanobacteria based photosynthetic production of sucrose: development and prospect

摘要:

生物炼制技术体系是缓解能源和环境危机，推动社会可持续发展的重要选择，而充足的糖原料供应是生物炼制的基础。蓝细菌光驱固碳合成蔗糖是一种潜力巨大的新型糖原料供应路线。基于高效的蓝细菌光驱固碳细胞工厂，可以在单平台上以太阳能为驱动将二氧化碳和水直接转化为蔗糖，过程简单、产品明确、易于提取，而且可以同时达到固碳减排和供应糖原料的效果，具有重要的研究和应用价值。本文回顾了蓝细菌光驱固碳合成蔗糖技术的发展现状，从合成机制、代谢工程策略、技术延伸应用等层面对其最新进展和所遇到的问题进行了总结介绍，并对该技术未来发展方向进行了展望。

关键词:蓝细菌，蔗糖，光合作用，代谢工程，盐胁迫

Abstract:

Biorefinery technologies provide promising solutions to achieve sustainable development facing energy and environment crisis, while abundant sugar feedstock is an essential basis for biorefinery industries. Photosynthetic production of sucrose with cyanobacteria is an alternative sugar feedstock supply route with great potentials. Driven by solar energy, cyanobacteria photosynthetic cell factory could directly convert carbon dioxide and water into sucrose, and such a process could simultaneously reduce carbon emissions and supply sugar feedstocks. Here we introduced the history and updated the state-of-the-art on development of cyanobacteria cell factories for photosynthetic production of sucrose, summarized the progress and problems on mechanisms of sucrose synthesis, metabolic engineering strategies and technology expansions, and finally forecasted the future development direction in this area.

Key words:cyanobacteria, sucrose, photosynthesis, metabolic engineering, salt stress