食源性致病菌群体感应信号分子的检测

Progress in detection and modeling of quorum sensing molecules of foodborne pathogens

摘要:

群体感应 (Quorum sensing，QS) 在食物中毒导致的食源性疾病暴发机制和食物腐败变质中起主要作用，QS影响致病菌的细胞被膜形成和致病性。文中通过深入了解食源性致病菌的QS信号分子，综述了革兰氏阴性和革兰氏阳性菌产生的信号分子类型，同时介绍了检测QS信号分子的不同技术，并根据QS机制在食品中的影响提出了思考和建议，为监控食源性致病菌提供依据。

Abstract:

Quorum sensing (QS) plays a major role in the outbreak mechanism of foodborne diseases caused by food poisoning and food spoilage. QS affects the formation of cell membrane and pathogenicity ofpathogenic bacteria. Through the in-depth understanding of QS molecules of food-borne pathogens, we describe here the types of signal molecules produced by Gram-negative and Gram-positive bacteria, and the differences in QS molecules. Meanwhile, we introduce the detection of QS molecules by different technologies. According to the influence of QS on food, we propose also future research needs for the control of foodborne pathogenic bacteria.