微生物与生命健康专题序言

Preface for special issue on microbiome and human health

摘要:

人体微生物组是指人体内由微生物组成的共生生态群落，其动态平衡与人体健康密切相关。微生物组被公认为可在人体中起调节免疫、代谢、消化吸收作用的重要“器官”，可与包括肺、肠道、阴道、大脑在内的多个器官产生联系，并逐步成为治疗癌症、冠心病、神经系统疾病等疑难杂症的潜在靶点。近年来，随着微生物组测序与分析技术的飞速发展，从微生物组角度发现人体微生物与多种疾病的关系并探索新的治疗方法已成为国际科研的热点与前沿。为了进一步促进人体微生物在生命健康领域的研究，《生物工程学报》特组织出版专题，重点阐述了人体微生物组的研究方法、人体微生物组与疾病以及干预方法等方面的研究进展，为推动微生物组在生命健康领域的快速发展提供理论基础。

Abstract:

Human microbiome is comprised of symbiotic microorganisms in the human body, whose dynamic balance is closely related to human health, and is recognized as important “organs” that can regulate immunity, metabolism and other aspects in human body, and is associated with functions of many organs including lung, intestine, vagina and brain, becoming a potential target for the treatment of cancer, coronary heart disease, neurological diseases and other difficult diseases. In recent years, with the rapid development of microbiome sequencing and analysis technology, it has become an international focus and forefront to discover the relationship between human microorganisms and many diseases, as well as target for new treatment methods. Thus, we organized this special issue and publish reviews on study methodology, human disease and microbiome as well as therapeutic strategies, and provide important information to advance microbiome research in China.