Abstract:In the “Tutorial for outline of the healthy China 2030 plan”,biomedicine was listed as a key planning and development area.Shanghai government also lists biomedicine as an emerging pillar industry.The rapid development of biomedicine industry put higher requirement for talents.Taking the idea of cross integration,mutually beneficial development,inheritance and innovation,the School of Biotechnology of East China University of Science and Technology organically integrates bioengineering and pharmaceutical majors to develop a new undergraduate engineering program of biomedicine,which specially reforms the talent training practice from the aspects of developing a “trinity teaching” standard system,a “three integration,three convergence” curriculum system,and a “three comprehensive education” innovative talent training system.We put forward the trinity of “value guidance,knowledge system,technology and non-technical core competence literacy” to foster emerging biomedicine engineering talents,and developed a comprehensive innovative talents training mode featured by “covering class-in and class-out,covering every student,and covering ideology and curriculum”.Moreover,we established effective connections between courses and training goals,between general education courses and professional courses,and between top-notch talent training systems and training programs.Based on the achievements of teaching reform of the emerging engineering program “intelligent bio-manufacturing”,the experience we obtained may provide ideas for development of the first-class bioengineering major in China.