Abstract:Bio-separation engineering"is a compulsory course for undergraduate students majored in bioengineering,and an important part of the"emerging engineering education "system for bioengineering.Our teaching team follows the principle of" student development as the center,innovation thinking as the core".Guided by the concept of "learning achievement" ,we reconstructed the teaching contents of this course,and carried out the teaching reform aiming at solving several long-standing problems.These include,for instance,the theoretical teaching is separated from the experimental practice,and students cannot internalize the theoretical knowledge into practical ability in time.Moreover,the contents of course is out-of-date and out of line with industry demand,the teaching form and assessment methods are relatively single,and the students'professional ability and quality are not effectively cultivated.In the new curriculum system,in which the"online"and "offline" teaching are both applied,we broke the boundary between theoretical and experimental courses,and made the contents keep up with the forefront of industry development through research-based teaching.In terms of teaching methods and teaching evaluation,we made full use of modern information technology to enrich classroom teaching activities,and carried out complete,dynamic and diversified assessment for students.These teaching reform measures greatly improved the students'interest in learning this course,as well as their professionalism and research ability.