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2025年3月13日 11:49 星期四
首页 > 过刊浏览>2022年第38卷第5期 >1809-1823. DOI:10.13345/j.cjb.210834
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受体介导的鳞翅目昆虫对Bt毒素抗性机制进展
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湖北省自然科学基金（2020CFB145）；国家自然科学基金（32102289）；湖北省教育厅科学技术研究项目（B2021289）


Advances in receptor-mediated resistance mechanisms of Lepidopteran insects to Bacillus thuringiensis toxin
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    摘要:

    苏云金芽孢杆菌作为一种对人畜安全、环境友好型绿色杀虫剂在全球被广泛使用。Bt毒素与昆虫中肠上特定毒素受体结合并发挥作用，形成毒素穿孔导致昆虫死亡是其重要的杀虫机制之一，靶标害虫对Bt毒素产生抗性是制约转Bt作物长期有效种植和Bt毒素持续使用的重要因素。文中从鳞翅目昆虫中肠细胞Bt毒素重要受体的研究阐述昆虫对Bt的抗性机制，为Bt抗性机制的深入研究和对害虫的防控与治理提供了一定的理论参考。

    Abstract:

    Bacillus thuringiensis is widely used as an insecticide which is safe and environmentally friendly to humans and animals. One of the important insecticidal mechanisms is the binding of Bt toxins to specific toxin receptors in insect midgut and forming a toxin perforation which eventually leads to insect death. The resistance of target pests to Bt toxins is an important factor hampering the long-term effective cultivation of Bt crops and the continuous use of Bt toxins. This review summarizes the mechanism of insect resistance to Bt toxins from the perspective of important Bt toxin receptors in midgut cells of Lepidopteran insects, which may facilitate the in-depth study of Bt resistance mechanism and pest control.

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刘磊磊,徐培文,刘凯于,魏巍,常忠燊,程大辉. 受体介导的鳞翅目昆虫对Bt毒素抗性机制进展[J]. 生物工程学报, 2022, 38(5): 1809-1823

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