Abstract:Industrial biotechnology is the application of biotechnology for the large-scale processing and production of chemicals, pharmaceuticals, fuels, materials, food and other products required by human society with microorganisms or enzymes as catalysts. The development of industrial biotechnology is the key path enabling the transition from fossil economy to bioeconomy. It will bring sustainable solutions to the natural resource use, energy supply and environmental protection currently faced by mankind. Tianjin Institute of Industrial Biotechnology of the Chinese Academy of Sciences is the main representative of China’s industrial biotechnology and biomanufacturing. Based on the development of the institute in the past decade, this review summarizes the strategic plan, important technological breakthroughs and industry impacts of China’s industrial biotechnology development, and prospects future development of industrial biotechnology and biomanufacturing in China.