“酶工程”国家一流本科课程的建设与探索

Development and exploration of the national first-class undergraduate course in "Enzyme Engineering"

摘要:

生物技术产业是我国战略性新兴产业，在整个国民经济中占有重要地位，创新型的高素质专业人才的培养意义重大。“酶工程”作为生物技术专业核心课程，教学质量的好坏直接影响学生质量及行业发展。本课程针对目前课程教学中存在的课程内容优化不足、过分依赖教材、教学方法单一等问题，以调整大纲、更新案例素材库、调动学生积极性为抓手，通过立体式教学-线上线下结合、互动式教学-翻转课堂、启发式教学-基于问题的学习(problem-based learning, PBL)教学模式、专题式教学-案例教学和完善考核机制等多种手段，激发学生的学习热情与创新能力，以培养厚基础、强实践的高素质专业人才。通过教学探索与实践，教学效果改善明显，学生的工程实践能力和创新能力得到了极大程度的提高。

关键词:酶工程;生物技术;教学内容;教学方法

Abstract:

The biotechnology industry is a strategic emerging industry in our country, holding a crucial position in the national economy. The training of innovative high-quality professionals carries immense significance. As the cornerstone course in biotechnology, "Enzyme Engineering" directly impacts the students' caliber and industry development. This course aims to address pertinent issues present in the current curriculum delivery, such as inadequately optimized content, excessive dependency on textbooks, and reliance on monotonous teaching methods. By adjusting the course outline, updating the case material repository, and engaging students' enthusiasm, we developed a three-dimensional approach to instruct. This approach included a blend of online and offline components, interactive teaching through the flipped classroom methodology, heuristic teaching using problem-based learning (PBL) mode, and topic teaching via case studies. We also improved the assessment mechanism to stimulate students' enthusiasm for learning nurture their innovation capabilities. Our objective was to foster high-quality professionals with a robust foundation and practical expertise. Through teaching exploration and practice, we have witnessed significant improvement in both teaching efficacy and students' engineering practice and innovation abilities.

Key words:enzyme engineering;biotechnology;teaching content;teaching method