2-苯乙醇合成研究进展

Advances in synthesis of 2-phenylethanol

摘要:

2-苯乙醇(2-phenylethanol, 2-PE)是一种具有玫瑰花香的芳香族醇，是全球用量第二大的香料物质，被广泛应用于化妆品、食品和医药等行业。本文介绍了2-苯乙醇的化学合成方法及其在植物和微生物中的合成路径，总结了提高微生物合成2-苯乙醇的策略，综述了微生物从头合成2-苯乙醇的研究进展，并对2-苯乙醇合成研究前景进行展望，以期为工业化生产2-苯乙醇提供一定理论基础。

Abstract:

2-phenylethanol (2-PE), an aromatic alcohol with a rose fragrance, is the second most widely used flavoring substance in the world. It is widely used in the cosmetic, food, and pharmaceutical industries. This paper introduces the chemical synthesis methods of 2-PE and the synthetic pathways in plants and microorganisms, summarizes the strategies to improve the microbial synthesis of 2-PE, reviews the research progress in de novo synthesis of 2-PE in microorganisms, and makes an outlook on the research prospects, aiming to provide a theoretical basis for the industrial production of 2-PE.