Interaction between Mycoplasma hyopneumoniae and host—a review

Abstract:

Mycoplasma hyopneumoniae is the pathogen of porcine enzootic pneumonia (PEP). Due to difficulties in studying the pathogenesis of M. hyopneumoniae for blockage on the establishment of gene operation platform and immature animal model, mycoplasmologists still make progress in understanding the interaction between M. hyopneumoniae and host. In this paper, we review the adhesion and damage of M. hyopneumoniae to host cells, the inflammatory response and immune response of host stimulated by M. hyopneumoniae. Meanwhile, we propose research directions of the pathogenesis of M. hyopneumoniae in the future. This review can provide references for the follow-up study on the interaction between M. hyopneumoniae and host, and provide theoretical basis for effective vaccine and drug development.