啤酒酵母细胞壁环境压力应答机制研究进展

Progress in brewer’s yeast cell wall stress response

摘要:

酵母细胞壁在细胞形态学的建立和维持中起重要作用，有助于细胞抵御环境变化。细胞壁主要由β-葡聚糖、甘露糖蛋白和几丁质组成，其组成和结构会由于压力胁迫发生动态重构。同时为了适应环境压力变化，啤酒酵母细胞壁在长期驯化过程中表现出相关压力应答机制。文中介绍了啤酒酵母细胞壁组成与结构，并综述了细胞壁重构与信号通路调控的分子机制。

Abstract:

Yeast cell wall plays an important role in the establishment and maintenance of cell morphology upon the cell wall stress. The cell wall of yeast consists of β-glucans, mannoproteins and chitin. The composition and structure remodel due to cell wall stress. Brewer’s yeast cell wall exhibits stress response during long-term acclimation in order to adapt to environmental changes. This paper reviews the composition and structure of yeast cell wall and the molecular mechanisms of cell wall remodeling and signal pathway regulation.